| 宋世宇1，侯娜莉2▲，朱桂启2，马新美2，张华2，刘利鹏2.原发性干燥综合征伴中枢及周围神经病变1例[J].中国医药科学,2025,(2):181-184 基金项目:山东省枣庄市卫生科技发展计划（202022） |
| 原发性干燥综合征伴中枢及周围神经病变1例 |
| A case of primary Sjogren’s syndrome with central and peripheral neuropathy |
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| DOI： |
| 中文关键词: 干燥综合征；中枢神经；周围神经；免疫球蛋白 |
| 英文关键词:Sjogren’s syndrome; Central nervous system; Peripheral nerve; Immunoglobulin |
| 作者 | 单位 | | 宋世宇1，侯娜莉2▲，朱桂启2，马新美2，张华2，刘利鹏2 | 1.济宁医学院临床医学院，山东济宁 272067；2.济宁医学院附属枣庄市立医院，山东枣庄 277100 |
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| 中文摘要: |
| [摘要] 原发性干燥综合征（pSS）是一种主要以高度淋巴细胞浸润及外分泌腺受累为特征的自身免疫疾病，部分pSS患者可出现中枢和/或周围神经损害。中枢及周围神经损害表现多种多样，如头痛、认知障碍、感觉共济失调、肢体麻木疼痛等。目前国内外关于干燥综合征合并中枢及周围神经病变报道不多。本文报道1例以反复周围及中枢神经系统受累为主要表现的干燥综合征，旨在提高对pSS相关神经系统损害的认识，减少误诊和漏诊。 |
| 英文摘要: |
| [Abstract] Primary Sjogren’s syndrome (pSS) is an autoimmune disease characterized by high lymphocyte infiltration and exocrine gland involvement. Some pSS patients may have central and/or peripheral nerve damage. There are various manifestations of central and peripheral nerve damage, such as headache, cognitive impairment, sensory ataxia, numbness and pain in limbs, etc. At present, there are few reports about Sjogren’s syndrome complicated with central and peripheral neuropathy at home and abroad. This paper reports a case of Sjogren’s syndrome with recurrent peripheral and central nervous system involvement, aiming at improving the understanding of pSS-related nervous system damage and reducing misdiagnosis and missed diagnosis. |
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