| 姜若曦1，杨少娣1，马丽慧1，曾海丽1，黄丽茹1，陆惠慧2▲.冠状动脉旁路移植术后发生低心排综合征危险因素的meta分析[J].中国医药科学,2025,(2):79-83 基金项目:广东省清远市社会发展领域自筹经费科技计划项目（200727104561374） |
| 冠状动脉旁路移植术后发生低心排综合征危险因素的meta分析 |
| Meta-analysis of risk factors of low cardiac output syndrome after coronary artery bypass grafting |
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| DOI： |
| 中文关键词: 冠状动脉旁路移植术；低心排综合征；危险因素；meta分析 |
| 英文关键词:Coronary artery bypass grafting; Low cardiac output syndrome; Risk factors; Meta-analysis |
| 作者 | 单位 | | 姜若曦1，杨少娣1，马丽慧1，曾海丽1，黄丽茹1，陆惠慧2▲ | 1.广州医科大学附属清远医院 广东省清远市人民医院心脏大血管外科，广东清远 511500；2.广州医科大学附属清远医院 广东省清远市人民医院护理部，广东清远 511500 |
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| 中文摘要: |
| [摘要] 目的 通过meta分析探讨冠状动脉旁路移植（CABG）术后患者发生低心排血量综合征（LCOS）的危险因素。 方法 中、外文相关文献经过检索、筛选、资料提取、质量评价和meta分析。 结果 最终纳入14篇文献，涉及12 605例患者资料。meta分析结果显示三支血管病变[OR=1.12，95%CI（0.28，4.47）]差异无统计学意义（P > 0.05）。meta分析得出CABG术后发生LCOS的危险因素为心律失常[OR=7.22，95%CI（4.93，10.58）]、心肌梗死[OR=2.28，95%CI（1.65，3.14）]、糖尿病[OR=1.72，95%CI（1.45，2.04）]、脑梗死[OR=4.63，95%CI（2.01，10.65）]、紧急手术[OR=2.61，95%CI（2.24，3.04）]、急性肾功能衰竭[OR=3.80，95%CI（2.16，6.70）]、左心室射血分数低[OR=3.50，95%CI（2.17，5.66）]、年龄≥60岁[OR=2.47，95%CI（1.71，3.56）]、不完全血运重建[OR=0.33，95%CI（0.24，0.46）]、左主干病变[OR=1.97，95%CI（1.11，3.51）]、肌酐高[WMD=15.94，95%CI（7.26，24.61）]、术中失血量大[WMD=189.07，95%CI（148.07，230.07）]和手术时间长[WMD=0.68，95%CI（0.45，0.90）]。 结论 在当前现有证据情况下，meta分析得到13个CABG术后发生LCOS的有效危险因素。 |
| 英文摘要: |
| [Abstract] Objective To investigate the risk factors of low cardiac output syndrome (LCOS) after coronary artery bypass grafting (CABG) by meta-analysis. Methods Relevant documents in Chinese and foreign languages were searched, screened, extracted, evaluated and analyzed by meta-analysis. Results Finally, 14 articles were included, involving data from 12 605 patients. The meta-analysis results showed that there was no statistically significant difference (P > 0.05) in 3 vessel lesions (OR=1.12, 95%CI [0.28, 4.47]). Meta analysis showed that the risk factors for LCOS after CABG were in the following . They were arrhythmia (OR=7.22, 95%CI [4.93, 10.58]), myocardial infarction (OR=2.28, 95%CI [1.65, 3.14]), diabetes (OR=1.72, 95%CI [1.45, 2.04]), cerebral infarction (OR=4.63, 95% CI [2.01, 10.65]), emergency surgery (OR=2.61, 95%CI [2.24, 3.04]), acute renal failure (OR=3.80, 95%CI [2.16, 6.70]), left ventricular ejection low score (OR=3.50, 95%CI [2.17, 5.66]), age≥ 60 years (OR=2.47, 95%CI [1.71, 3.56]), incomplete revascularization (OR=0.33, 95%CI [0.24, 0.46]), left main artery disease (OR=1.97, 95%CI [1.11, 3.51]), high creatinine (WMD=15.94, 95%CI [7.26, 24.61]), large intraoperative hemorrhage (WMD=189.07, 95%CI [148.07, 230.07]) and long operation time (WMD = 0.68, 95%CI [0.45, 0.90]). Conclusion Based on the existing evidence, 13 effective risk factors of LCOS after CABG were obtained by meta-analysis. |
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