| 吴佳昕，林倩雯，文晓慧，顾晓锋▲.有氧及抗阻运动对前列腺癌内分泌患者肌力及疲劳影响[J].中国医药科学,2025,(2):61-65 基金项目:复旦大学-复星护理科研基金面上项目（FNF201837） |
| 有氧及抗阻运动对前列腺癌内分泌患者肌力及疲劳影响 |
| Effect of aerobic and resistance exercise on muscle strength and fatigue of patients with endocrine therapy for prostate cancer |
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| DOI： |
| 中文关键词: 有氧运动；抗阻运动；前列腺癌；内分泌治疗；肌力；疲乏 |
| 英文关键词:Aerobic exercise; Resistance exercise; Prostate cancer; Endocrine therapy; Muscle strength; Fatigue |
| 作者 | 单位 | | 吴佳昕，林倩雯，文晓慧，顾晓锋▲ | 复旦大学附属肿瘤医院护理部，上海 200032 |
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| 中文摘要: |
| [摘要] 目的 探讨运动干预对于前列腺癌内分泌治疗患者肌力减弱及疲劳状况的改善效果。 方法 选取2018年6月至2023年9月复旦大学附属肿瘤医院泌尿外科收治的60例前列腺癌内分泌治疗患者作为研究对象，按照随机数表法分为干预组和对照组，每组各30例。对照组予以常规护理，干预组在常规护理基础上实施为期12周的运动干预，包括有氧运动及抗阻训练。采用癌症疲乏量表（CFS）评估疲乏程度，采用握力计及30 s椅子站立试验评估患者上、下肢肌力，采用癌症患者生命质量测定量表（QLQ-C30）、汉化简化版扩展性前列腺癌复合指数量表（EPIC-26）评估患者生活质量。 结果 干预前，两组患者CFS评分、肌力及生活质量评分比较，差异均无统计学意义（P > 0.05）。干预后，干预组CFS评分、肌力及生活质量评分均优于对照组，差异有统计学意义（P < 0.05）。 结论 对前列腺癌内分泌患者采取有氧运动及抗阻训练可有效改善患者肌力，减少疲劳程度，提高患者生活质量。 |
| 英文摘要: |
| [Abstract] Objective To explore the effect of exercise intervention on muscle weakness and fatigue in patients with endocrine therapy for prostate cancer. Methods From June 2018 to September 2023, 60 patients with endocrine therapy for prostate cancer were selected as the research subject, and were randomly divided into intervention group and control group with 30 cases in each group. The control group was given routine care, while the intervention group was given exercise intervention for 12 weeks on the basis of routine care, including aerobic exercise and resistance training. Cancer fatigue scale (CFS) was used to evaluate the degree of fatigue, grip strength meter and 30-second chair standing test were used to evaluate the muscle strength of upper and lower limbs, and the european organization for research and treatment of cancer quality of life questionnaire (QLQ-C30) and abbreviated version of the expanded prostate cancer index composite instrument (EPIC-26) were used to evaluate the quality of life of patients. Results Before the intervention, there was no significant difference in CFS score, muscle strength and quality of life score between the two groups (P > 0.05). After the intervention, the scores of CFS, muscle strength and quality of life in the intervention group were better than those in the control group, and the difference between the two groups was statistically significant (P < 0.05). Conclusion Aerobic and resistance exercise for patients with endocrine therapy for prostate cancer can effectively improve their muscle strength, reduce fatigue and improve their quality of life. |
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