| 陈鑫1，霍大勇1▲，王雪飞2，张建勋1.基于血流动力学、镇痛效果分析右美托咪定用于老年患者髋部骨折术的效果[J].中国医药科学,2025,(2):49-52 基金项目:吉林省中医药科技项目（2024302） |
| 基于血流动力学、镇痛效果分析右美托咪定用于老年患者髋部骨折术的效果 |
| Analysis on the effect of dexmedetomidine on hip fracture surgery in elderly patients based on hemodynamics and analgesic effect |
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| DOI： |
| 中文关键词: 血流动力学；镇痛效果；髋部骨折术；右美托咪定 |
| 英文关键词:Hemodynamics; Analgesic effect; Hip fracture surgery; Dexmedetomidine |
| 作者 | 单位 | | 陈鑫1，霍大勇1▲，王雪飞2，张建勋1 | 1.吉林省吉林中西医结合医院麻醉科，吉林吉林 132000；2.吉林省吉林中西医结合医院肛肠科，吉林吉林 132000 |
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| 中文摘要: |
| [摘要] 目的 基于血流动力学、镇痛效果分析右美托咪定用于老年患者髋部骨折术的效果。 方法 选取吉林省吉林中西医结合医院2021年1月至2023年1月收治的髋部骨折老年患者84例，采用随机数表法将其分为对照组（n=42）和观察组（n=42）。两组患者均采用麻醉诱导行髋部骨折术，在此基础上，对照组联合静脉输注0.9%的生理盐水，观察组联合静脉输注同等剂量的右美托咪定。比较两组的围手术期指标（麻醉时间、术中输液量、术中出血量）、术后血流动力学（平均动脉压、动脉舒张压、动脉收缩压、心率）、疼痛视觉模拟评分法（VAS）评分变化及术后并发症情况（低血压、咳嗽、呕吐、心动过缓）。 结果 两组的麻醉时间、术中输液量、术中出血量比较，差异无统计学意义（P > 0.05）。两组的血流动力学指标和疼痛均随着时间变化而变化，且观察组的血流动力学指标和疼痛小于对照组，差异有统计学意义（P < 0.05）。观察组的术后并发症总发生率低于对照组，差异有统计学意义（P < 0.05）。 结论 老年髋关节骨折术患者在手术期间使用右美托咪定，可以显著减轻术后疼痛，确保血流动力学稳定，且安全性高。因此，右美托咪定值得在老年髋关节骨折术中广泛应用。 |
| 英文摘要: |
| [Abstract] Objective To analyze the effect of dexmedetomidine on hip fracture surgery in elderly patients based on hemodynamics and analgesic effect. Methods A total of 84 elderly patients with hip fracture admitted to and treated in the Jilin Integrated Traditional Chinese and Western Medicine Hospital from January 2021 to January 2023 were selected and divided into the control group (n=42) and the observation group (n=42) according to the random number table method. Patients in both groups underwent hip fracture surgery under anesthesia induction. On this basis, the control group was combined with intravenous infusion of 0.9% normal saline, while the observation group was combined with intravenous infusion of the same dose of dexmedetomidine. The perioperative indices (anesthesia time, intraoperative infusion volume and intraoperative hemorrhage volume), postoperative hemodynamics (mean arterial pressure, diastolic arterial pressure, systolic arterial pressure and heart rate), visual analogue scale (VAS) pain score changes and postoperative complications (hypotension, cough, vomiting and bradycardia) were compared between the two groups. Results There were no statistically significant differences in anesthesia time, intraoperative infusion volume and intraoperative hemorrhage volume between the two groups (P > 0.05). The hemodynamics indices and pain in the two groups all changed with time, and the hemodynamics indices and pain in the observation group were smaller than those in the control group, with statistically significant differences (P < 0.05). The total incidence of postoperative complications in the observation group was lower than that in the control group, with statistically significant differences (P < 0.05). Conclusion The use of dexmedetomidine in elderly patients with hip fracture during surgery can significantly reduce postoperative pain, ensure hemodynamic stability, and has high safety. Therefore, dexmedetomidine deserves to be widely applied in the hip joint fracture surgery of the elderly. |
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