| 李强1，邝生2，马荣1，李燕利1，李梦丽1，朱艳春1，钱冬梅1，常晓红1.胆结石患者经特定食物测定胆囊功能后选择性经胃镜保胆取石术的临床应用[J].中国医药科学,2024,14(11):195-198 基金项目:新疆生产建设兵团第二师铁门关市科技计划项目（2022SFGG05） |
| 胆结石患者经特定食物测定胆囊功能后选择性经胃镜保胆取石术的临床应用 |
| Clinical application of selective endoscopic transgastric gallbladder-preserving cholecystolithotomy in patients with gallstones after measuring gallbladder function with specific food |
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| DOI： |
| 中文关键词: 胆结石；特定食物；胆囊功能；经胃镜保胆取石术 |
| 英文关键词:Gallstones; Specific food; Gallbladder function; Endoscopic transgastric gallbladder-preserving cholecystolithotomy |
| 作者 | 单位 | | 李强1，邝生2，马荣1，李燕利1，李梦丽1，朱艳春1，钱冬梅1，常晓红1 | 1.新疆生产建设兵团第二师库尔勒医院消化科，新疆库尔勒 841000；
2.江苏省昆山市第六人民医院消化科，江苏昆山 215300 |
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| 中文摘要: |
| [摘要] 目的 探讨胆结石患者经特定食物测定胆囊功能后选择性经胃镜保胆取石术的临床效果。 方法 回顾收集新疆生产建设兵团第二师库尔勒医院2021年9月至2023年6月收治的80例胆结石患者资料，全部患者治疗前均经特定食物测定胆囊功能，并根据胆囊功能选取治疗方式，按患者不同治疗方式分为对照组（37例，内科保守药物治疗；胆囊收缩率40%～79%，伴有轻度症状）、治疗组（53例，经胃镜保胆取石术；胆囊收缩率40%～59%，胆囊壁厚度≤3 mm）；比较两组胆囊收缩功能、结石清除效果。 结果 治疗组治疗1、3、6个月的胆囊收缩率、胆囊排空率高于治疗前，且高于对照组，差异有统计学意义（P < 0.05）；对照组治疗前，治疗1、3、6个月的胆囊收缩率、胆囊排空率比较，差异无统计学意义（P > 0.05）；治疗组结石清除效果优于对照组，差异有统计学意义（P < 0.05）。 结论 胆结石患者经特定食物测定胆囊功能后选择性经胃镜保胆取石术治疗可改善胆囊收缩功能，且结石清除效果好。 |
| 英文摘要: |
| [Abstract] Objective To investigate the clinical efficacy of selective endoscopic transgastric gallbladder-preserving cholecystolithotomy in patients with gallstones after measuring gallbladder function with specific food. Methods The data of 80 patients with gallstones admitted to Korla Hospital, the Second Division of Xinjiang Production and Construction Corps from September 2021 to June 2023 were retrospectively collected. All patients were tested for gallbladder function by specific food before treatment, and the treatment methods were selected according to the gallbladder function. According to different treatment methods, the patients were divided into the control group (n=37, treated with conservative drugs in internal medicine. Gallbladder contraction rate 40%-79%, accompanied by mild symptoms) and the treatment group (n=53, underwent endoscopic transgastric gallbladder-preserving cholecystolithotomy. Gallbladder contraction rate 40%-59%, gallbladder wall thickness≤ 3 mm). The gallbladder contraction function and stone removal effect were compared between the two groups. Results The gallbladder contraction rate and gallbladder emptying rate in the treatment group after 1 month, 3 months and 6 months of treatment were higher than those before treatment and higher than those in the control group, with statistically significant differences (P < 0.05). In the control group, there were no statistically significant differences in gallbladder contraction rate and gallbladder emptying rate before treatment, and 1 month, 3 months and 6 months after treatment (P > 0.05).The effect of removing stones in the treatment group was superior to that in the control group, with statistically significant difference (P < 0.05). Conclusion The selective endoscopic transgastric gallbladder-preserving cholecystolithotomy in patients with gallstones after measuring gallbladder function with specific food can improve the gallbladder contraction function, and the stone removal effect is good. |
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