| 黄玉婷1△，谭怡丝2，李元聪3，谭劲3▲.中西医结合治疗糜烂型口腔扁平苔藓的临床观察[J].中国医药科学,2024,14(11):116-119 基金项目:国家自然科学基金面上项目（82374530；81874496） |
| 中西医结合治疗糜烂型口腔扁平苔藓的临床观察 |
| Clinical observation on treatment of erosive oral lichen planus with integrated traditional Chinese and western medicine |
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| DOI： |
| 中文关键词: 糜烂型口腔扁平苔藓；脾胃湿热型；中西医结合；糖皮质激素 |
| 英文关键词:Erosive oral lichen planus; Damp-heat in spleen and stomach; Integrated traditional Chinese and western medicine; Glucocorticoid |
| 作者 | 单位 | | 黄玉婷1△，谭怡丝2，李元聪3，谭劲3▲ | 1.湖南中医药大学第一中医临床学院，湖南长沙 410000；2.湖南中医药大学中西医结合学院，
湖南长沙 410000；3.湖南中医药大学第一附属医院口腔科，湖南长沙 410000 |
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| 中文摘要: |
| [摘要] 目的 观察使用中药复方联合糖皮质激素含漱治疗糜烂型口腔扁平苔藓的效果。 方法 选择2022年1月至2023年6月湖南中医药大学第一附属医院口腔科门诊就诊的糜烂型口腔扁平苔藓患者56例，并随机分成两组，每组各28例，对照组选用糖皮质激素含漱治疗，治疗组在其基础上加用中药治疗，治疗30 d后，比较两组患者临床疗效、视觉模拟评分法（VAS）评分、糜烂面积、白纹面积及3个月后复发情况。 结果 两组疗效差异有统计学意义（P < 0.05），治疗组优于对照组；治疗后，两组VAS评分、糜烂面积低于治疗前，治疗组白纹面积低于治疗前，且治疗组的糜烂面积和白纹面积均低于对照组，差异有统计学意义（P < 0.05）；治疗组复发率低于对照组，差异有统计学意义（P < 0.05）。 结论 中西医结合治疗糜烂型口腔扁平苔藓效果较好。 |
| 英文摘要: |
| [Abstract] Objective To observe the therapeutic effect of using traditional Chinese medicine compound integrated with glucocorticoid mouthwash in the treatment of erosive oral lichen planus. Methods A total of 56 patients with erosive oral lichen planus were selected from the Department of Stomatology of the First Affiliated Hospital of Hunan University of Chinese Medicine, from January 2022 to June 2023. They were randomly divided into two groups, with 28 cases in each group. The control group was treated with glucocorticoid gargle, while the treatment group was treated with traditional Chinese medicine on the basis of it. After 30 days of treatment, the clinical efficacy, visual analogue scale (VAS) score, erosive area, white stripe area, and recurrence rate after 3 months were compared between the two groups. Results The difference of effective rate between two groups was statistically significant (P < 0.05)，and the treatment group was superior to that of the control group. After treatment, the VAS score and erosion area of the two groups were lower than before treatment, and the white stripe area of the treatment group was lower than before treatment. Moreover, the erosion area and white stripe area of the treatment group were lower than those of the control group, and the difference was statistically significant (P < 0.05). The recurrence rate of the treatment group was lower than that of the control group, and the difference was statistically significant (P < 0.05). Conclusion The integrated traditional Chinese and western medicine is effective in treating erosive oral lichen planus. |
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