| 吴明华.中青年冠心病患者冠状动脉多支病变的影响因素分析[J].中国医药科学,2024,14(10):128-131 基金项目: |
| 中青年冠心病患者冠状动脉多支病变的影响因素分析 |
| Analysis of impacting factors of coronary artery multi-vessel lesions in young and middle-aged patients with coronary heart disease |
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| DOI： |
| 中文关键词: 冠心病；多支病变；中青年；影响因素 |
| 英文关键词:Coronary heart disease; Multi-vessel lesion; Young and middle-aged patients; Impacting factors |
| 作者 | 单位 | | 吴明华 | 江西省九江市柴桑区人民医院心内科，江西九江 332100 |
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| 中文摘要: |
| [摘要] 目的 探讨中青年冠心病患者冠状动脉多支病变的影响因素。 方法 连续性选取 2020 年 1 月至 2022 年 12 月在九江市柴桑区人民医院心内科住院的 60 岁以下冠心病患者 400 例为研究对象。研究对象分为冠状 动脉单支病变组和多支病变组，采用 logistic 回归分析多支病变的影响因素。 结果 与冠状动脉单支病变组 比较，多支病变组中高血压、糖尿病、血脂异常、吸烟、肥胖者较多，同型半胱氨酸、甘油三酯、总胆固醇、低 密度脂蛋白胆固醇、促甲状腺生成素、游离三碘甲状腺素原、天冬氨基酸转移酶、红细胞分布宽度均较高（P < 0.05）。高血压、糖尿病、血脂异常、吸烟、肥胖及较高的红细胞分布宽度是中青年冠心病患者冠状动脉 多支病变的独立危险因素（P < 0.05）。 结论 中青年冠心病患者应加强危险因素评估，降低冠状动脉多支病 变的发生风险。 |
| 英文摘要: |
| [Abstract] Objective To investigate the impacting factors of coronary artery multi-vessel lesions in young and middle-aged patients with coronary heart disease. Methods A total of 400 patients with coronary heart disease under the age of 60 who were hospitalized in the Department of Cardiology, Jiujiang Chaisang District People's Hospital from January 2020 to December 2022 were continuously collected as the research object. The subjects were divided into the coronary artery single-vessel lesion group and the multi-vessel lesions group. The impacting factors of multi-vessel lesions were analyzed by using logistic regression. Results Compared with the coronary artery single-vessel lesion group, patients with hypertension, diabetes, dyslipidemia, smoking and obesity were more in the multi-vessel lesions group, and the homocysteine, triacylglycerol, total cholesterol, low-density lipoprotein cholesterol, thyrotropin, free triiodo thyroxine, aspartate aminotransferase and red blood cell distribution width were all higher (P < 0.05). Hypertension, diabetes, dyslipidemia, smoking, obesity, and relatively high red blood cell distribution width were independent risk factors for coronary artery multi-vessel lesions in young and middle-aged patients with coronary heart disease (P < 0.05). Conclusion Young and middle-aged patients with coronary heart disease should strengthen the assessment of risk factors to reduce the risk of coronary artery multi-vessel lesions. |
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