刘伟1,任春慧2,常文轩1,宫雪梅1,冯晨1,张晓鹏1,程琳1,毕博昊1,穆实1,朱敏2▲.磁共振3D-ASL技术联合ABCD2评分在前循环短暂性脑缺血发作中应用价值分析[J].中国医药科学,2024,14(7):144-148 基金项目:黑龙江省属高等学校基本科研业务费科研项目(2021-KYYWF-0497;2022-KYYWF-0692) |
磁共振3D-ASL技术联合ABCD2评分在前循环短暂性脑缺血发作中应用价值分析 |
Analysis of the application value of magnetic resonance 3D-ASL technology combined with ABCD2 score in transient ischemic attacks of the anterior circulation |
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DOI: |
中文关键词: 三维动脉自旋标记;ABCD2评分;短暂性脑缺血发作;脑梗死 |
英文关键词:Three-dimensional arterial spin labeling; ABCD2 score; Transient ischemic attack; Cerebral infarction |
作者 | 单位 | 刘伟1,任春慧2,常文轩1,宫雪梅1,冯晨1,张晓鹏1,程琳1,毕博昊1,穆实1,朱敏2▲ | 1.牡丹江医学院研究生处,黑龙江牡丹江 157011;2.牡丹江医学院附属红旗医院磁共振科,黑龙江牡丹江 157011 |
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中文摘要: |
[摘要]目的 探讨三维动脉自旋标记(3D-ASL)技术联合ABCD2评分在前循环短暂性脑缺血发作(TIA)中的应用价值。方法 选择2021年5月至2022年12月在牡丹江医学院附属红旗医院确诊为前循环TIA的患者64例,完成各项磁共振检查,其中双时相3D-ASL标记后延迟时间(PLD)分别为1.5、2.5 s,完成ABCD2评分并进行为期90 d的随访。对3D-ASL图像进行分析,测量脑血流量(CBF)并计算相对脑血流量(rCBF),分析3D-ASL、ABCD2评分对TIA患者病情及预后的评估价值。结果 PLD=1.5 s CBF值、rCBF值均小于PLD=2.5 s;rCBF值与ABCD2评分呈负相关;3D-ASL对TIA患者异常检出率高于MRA;3D-ASL异常组脑梗死发生率高于正常组;不同ABCD2评分风险组脑梗死发生率比较,差异有统计学意义(P < 0.05);ROC曲线分析结果显示,3D-ASL联合ABCD2评分预测TIA患者90 d预后的曲线下面积(AUC)最大为0.907。结论 双时相3D-ASL能够发现TIA患者细微灌注改变,反映代偿情况,可作为TIA患者进一步检查的方式,联合ABCD2评分可以有效预测TIA患者90 d预后,具有较大的临床应用价值。 |
英文摘要: |
[Abstract] Objective To explore the application value of three dimensioned-arterial spin labeling (3D-ASL) technology in combination with ABCD2 score in the treatment of transient ischemic attack (TIA) of the anterior circulation. Methods A total of 64 patients diagnosed with TIA of the anterior circulation at Hongqi Hospital affiliated to Mudanjiang Medical University from May 2021 to December 2022 were selected. They completed various magnetic resonance imaging examinations, with the post label delay (PLD) of dual-phase 3D-ASL being 1.5 s and 2.5 s respectively, and completed the ABCD2 score as well as a 90-day follow-up. 3D-ASL images were analyzed, cerebral blood flow (CBF) was measured, and relative cerebralblood flow (rCBF) was calculated to analyze the application value of 3D-ASL and ABCD2 scores on evaluation of the conditions and prognosis of TIA patients. Results The PLD = 1.5 s, CBF and rCBF are both lower than PLD = 2.5 s. rCBF is negatively correlated with ABCD2 score. The 3D-ASL detection rate of abnormalities in TIA patients is higher than MRA detection rate. The incidence of cerebral infarction in the 3D-ASL detected abnormality group was higher than that in the normal group. There are differences in the incidence of cerebral infarction among different risk groups, with a statistically significant difference. The ROC curve analysis results show that the combination of 3D-ASL technology and ABCD2 score has the maximum area under the curve (AUC) of 0.907 for the 90-day prognosis of TIA patients. Conclusion Dual-phase 3D-ASL can detect subtle perfusion changes in TIA patients, reflect compensatory blood supply conditions, and serve as a further examination method for TIA patients. In combination with ABCD2 score, dual-phase 3D-ASL can effectively predict the 90-day prognosis of TIA patients and has significant clinical application value. |
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