| 江雪纯，范丽花，尹墨青，陈赟虎，洪程▲.太仓市某医院高血压病肾损害患者中医证型与肾功能损伤程度分析[J].中国医药科学,2024,14(7):104-108 基金项目:江苏省太仓市科技计划项目（TC2021JCYL23） |
| 太仓市某医院高血压病肾损害患者中医证型与肾功能损伤程度分析 |
| Analysis of traditional Chinese medicine syndrome types and degree of renal function damage in patients with renal damage after hypertension at a certain hospital in Taicang City |
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| DOI： |
| 中文关键词: 高血压；肾损害；太仓地区；中医证型 |
| 英文关键词:Hypertension; Renal damage; Taicang area; Traditional Chinese medicine syndrome types |
| 作者 | 单位 | | 江雪纯，范丽花，尹墨青，陈赟虎，洪程▲ | 南京中医药大学太仓附属医院 太仓市中医医院心内科，江苏太仓 215400 |
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| 中文摘要: |
| [摘要] 目的 探究太仓地区高血压病肾损害中医证型与肾功能的关系。 方法 纳入2021年10月至2022年10月太仓市中医医院（本院）诊治的高血压病肾损害患者363例，根据患者年龄分为青年、中年、老年三组，统计分析不同年龄段中医证型与血压水平、肾功能损伤程度的相关性。 结果 太仓地区高血压病肾损害中医证型从高到低依次为脾肾两虚、肝肾阴虚、肝阳上亢、痰瘀互结，青年组以肝阳上亢型最多，中年组痰瘀互结型最少，其余各证型之间几乎持平，老年组以脾肾两虚最多，三组脾肾两虚、肝阳上亢占比比较，差异有统计学意义（P < 0.05）；三组痰瘀互结、肝肾阴虚占比比较，差异无统计学意义（P > 0.05）。三组血压比较，差异均有统计学意义（P < 0.05）。不同年龄段的肌酐、尿素氮比较，差异均有统计学意义（P < 0.05），但肾小球滤过率比较，差异无统计学意义（P > 0.05）。不同证型收缩压、舒张压比较，差异均有统计学意义（P < 0.05），但肌酐、尿微量白蛋白、24 h蛋白尿定量比较，差异均无统计学意义（P > 0.05）。 结论 本院高血压病肾损害以老年患者为主，证型以脾肾两虚最多，不同年龄、证型在血压、肾功能等方面均存在一定差异，临床应做到因人而异，中青年患者早诊断、早干预，以防治疾病进展，老年患者应更加关注血压、肾功能损害程度。 |
| 英文摘要: |
| [Abstract] Objective To explore the relationship between traditional Chinese medicine (TCM) syndrome types of renal damage after hypertension and renal function in a certain hospital in Taicang area. Methods A total of 363 patients with renal damage after hypertension diagnosed and treated at Taicang Hospital of Traditional Chinese Medicine (our hospital) from October 2021 to October 2022 were included. They were divided into three groups based on their age: young, middle-aged, and elderly. The correlation between TCM syndrome types, blood pressure levels, and degree of renal function damage in different age groups was statistically analyzed. Results The TCM syndrome types of renal damage after hypertension in the Taicang area, from high to low, were spleen and kidney deficiency, yin deficiency of the liver and kidney, liver yang hyperactivity, and binding of phlegm and stasis. The liver yang hyperactivity type was the most common in young group, while the middle-aged group has the least binding of phlegm and stasis, the other syndrome types were almost equal, and the spleen and kidney deficiency type was the most common in elderly group. There was a statistically significant difference in the proportion of spleen kidney deficiency and liver yang hyperactivity among the three groups (P < 0.05). There was no statistically significant difference in the binding of phlegm and stasis, and the yin deficiency of the liver and kidney among the three groups (P > 0.05). The blood pressure among the three groups was compared, with statistically significant difference (P < 0.05). The creatinine and urea nitrogen were compared among different age groups, with statistically significant differences (P < 0.05), but the GFR was compared among different age groups, without statistically significant difference (P > 0.05). The systolic and diastolic blood pressure were compared among different syndrome types, with statistically significant differences (P < 0.05),but the creatinine, urinary microalbumin, and 24-hour proteinuria quantification were compared, without statistically significant differences (P > 0.05). Conclusion Renal damage after hypertension in our hospital in Taicang City mainly occurred in elderly patients, with spleen and kidney deficiency being the most common syndrome type. There are certain differences in blood pressure, renal function, and other aspects among different ages and syndrome types. Clinical practice should be personalized, with early diagnosis and intervention for middle-aged and young people to prevent and treat disease progression. For elderly patients, we should pay more attention to blood pressure and the degree of renal function damage. |
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