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孙丽君.腹腔镜肌瘤剔除术对患者术后卵巢储备功能、抗氧化水平的影响[J].中国医药科学,2022,(20):136-138        基金项目:
腹腔镜肌瘤剔除术对患者术后卵巢储备功能、抗氧化水平的影响
Effect of laparoscopic myomectomy on ovarian reserve function and antioxidant level in patients after operation
  
DOI:
中文关键词:  腹腔镜肌瘤剔除术;卵巢储备功能;抗氧化水平;并发症
英文关键词:Laparoscopic myomectomy; Ovarian reserve function; Antioxidant level; Complication
作者单位
孙丽君 南京市江宁医院妇科,江苏南京 211199 
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中文摘要:
      [摘要] 目的 探究腹腔镜肌瘤剔除术对患者术后卵巢储备功能、抗氧化水平的影响。 方法 本研究选取2019年3月至2021年3月在南京医科大学附属江宁医院妇科就诊的120例子宫肌瘤患者作为研究对象,按照治疗方案分为对照组(n=54)、观察组(n=66)。对照组予以开腹子宫肌瘤切除术,观察组予以腹腔镜肌瘤剔除术,比较两组患者术后的卵巢储备功能、抗氧化水平以及并发症的发生情况。 结果 术后,观察组卵巢储备功能中的雌二醇(E2)、抗米勒管激素(AMH)高于对照组,促卵泡生成素(FSH)低于对照组(P < 0.05);观察组环磷酰胺水平高于对照组,而肌红蛋白低于对照组(P < 0.05);观察组并发症总发生率低于对照组,差异有统计学意义(P < 0.05)。 结论 采用腹腔镜肌瘤剔除术的方式能够减少患者卵巢储备功能的影响,有效缓解其氧化受损情况,且促进术后恢复,显著提高了患者的生活质量。
英文摘要:
      [Abstract] Objective To explore the effect of laparoscopic myomectomy on ovarian reserve function and antioxidant level in patients after operation. Methods A total of 120 patients with hysteromyoma admitted to the Department of Gynecology of the Affiliated Jiangning Hospital of Nanjing Medical University from March 2019 to March 2021 were selected as the study subjects in this study. They were divided into the control group (n=54) and the observation group (n=66) according to the treatment regimen. With open myomectomy conducted in the control group and laparoscopic myomectomy conducted in the observation group, the occurrence of ovarian reserve function, antioxidant level and complications after operation of patients in the two groups were compared. Results After operation, estradiol (E2) and anti-Müllerian hormone (AMH) in ovarian reserve function in the observation group were higher than those in the control group, and follicle-stimulating hormone (FSH) was lower than that in the control group (P < 0.05). In the observation group, the level of cyclophosphamide was higher than that in the control group, while myoglobin was lower than that in the control group (P < 0.05). The total complication rate was lower in the observation group than that in the control group, with statistically significant differences (P < 0.05). Conclusion Laparoscopic myomectomy can reduce the effect on ovarian reserve function, effectively alleviate the oxidative damage, promote postoperative recovery, and significantly improve the quality of life of patients.
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