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陆洁雅.海昆肾喜胶囊治疗慢性肾功能衰竭的临床疗效[J].中国医药科学,2022,(4):74-76        基金项目:
海昆肾喜胶囊治疗慢性肾功能衰竭的临床疗效
Clinical efficacy of Haikun Shenxi Capsule in the treatment of chronic renal failure
  
DOI:
中文关键词:  慢性肾功能衰竭;海昆肾喜胶囊;生活质量;肾功能
英文关键词:Chronic renal failure; Haikun Shenxi Capsule; Quality of life; Renal function
作者单位
陆洁雅 江苏省宜兴市中医医院肾内科,江苏宜兴 214200 
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中文摘要:
      [摘要] 目的 研究分析慢性肾功能衰竭患者应用海昆肾喜胶囊治疗的效果。 方法 选取2018年1月至2020年12月宜兴市中医医院肾内科收治的96例慢性肾功能衰竭患者为研究对象,依据抽签法随机分为对照组与试验组。对照组(n=48)患者应用西医常规治疗,试验组(n=48)患者加用海昆肾喜胶囊治疗,以患者临床疗效、肾功能、生存质量为观察指标,统计比较两组观察结果。 结果 试验组临床总有效率高于对照组,差异有统计学意义(P < 0.05)。治疗前,试验组与对照组血尿素氮(BUN)、血肌酐(Scr)、24 h尿蛋白定量(24 h U-Pr)水平、肾小球滤过率(GFR)比较,差异无统计学意义(P > 0.05);治疗后,试验组BUN、Scr、24 h U-Pr水平均低于对照组,GFR大于对照组,差异有统计学意义(P < 0.05)。治疗前,试验组与对照组生理、心理、社会、环境评分比较,差异无统计学意义(P > 0.05);治疗后,试验组生理、心理、社会、环境评分高于对照组,差异有统计学意义(P < 0.05)。 结论 慢性肾功能衰竭患者应用海昆肾喜胶囊的治疗效果更显著,其有助于改善患者肾功能,提高患者生存质量,值得临床推荐应用。
英文摘要:
      [Abstract] Objective To study and analyze the efficacy of Haikun Shenxi Capsule in the treatment of patients with chronic renal failure. Methods A total of 96 Patients with chronic renal failure admitted to the Department of Nephrology, Yixing Traditional Chinese Medicine Hospital from January 2018 to December 2020 were selected as study subjects. They were randomly divided into the control group and the experimental group based on the drawing method. Patients in the control group (n=48) were treated with conventional western medicine, while patients in the experimental group (n=48) were treated with western medicine combined with Haikun Shenxi Capsule. The clinical efficacy, renal function and survival quality of patients were observed, and the observation results were statistically compared between the two groups. Results The total clinical effective rate of the experimental group was higher than that of the control group, with statistically significant difference (P < 0.05). Before treatment, there were no statistically significant differences between the experimental group and the control group in the levels of blood urea nitrogen (BUN), blood serum creatinine (Scr) and 24 h urine protein quantification (24 h U-Pr), and the glomerular filtration rate (GFR) (P > 0.05). After treatment, BUN, Scr and 24 h U-Pr levels in the experimental group were lower than those in the control group, and GFR was greater than that in the control group, with statistically significant difference (P < 0.05). Before treatment, there were no statistically significant differences between the experimental group and the control group in the physiological, psychological, social and environmental scores (P > 0.05). After treatment, the physiological, psychological, social and environmental scores of the experimental group were higher than those of the control group, with statistically significant differences (P < 0.05). Conclusion In the treatment of patients with chronic renal failure, Haikun Shenxi Capsule is much effective in improving renal function and enhancing the survival quality of patients, and is worthy of clinical recommendation and application.
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关键词: 中国医药科学 中国医学 中国医学科学 中华医学 医学杂志 临床医学杂志 医学期刊 中国预防医学 中华预防医学 预防医学杂志 中国药学 药学杂志
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