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范素贞,梁豪,王娟娟.右美托咪定应用于无痛胃镜中的麻醉治疗效果评价[J].中国医药科学,2021,(4):95-97        基金项目:
右美托咪定应用于无痛胃镜中的麻醉治疗效果评价
Evaluation of the anesthetic efficacy of dexmedetomidine applied in painless gastroscope
  
DOI:
中文关键词:  [关键词] 无痛胃镜;麻醉治疗;右美托咪定;丙泊酚
英文关键词:[Key words] Painless gastroscope; Anesthetic treatment; Dexmedetomidine; Propofol
作者单位
范素贞,梁豪,王娟娟 广东省惠州市第三人民医院麻醉科,广东惠州 516000 
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中文摘要:
      [摘要] 目的 探讨在无痛胃镜中应用右美托咪定加以麻醉治疗的临床效果。 方法 纳入2018年1月至2020年1月于惠州市第三人民医院接受无痛胃镜检查的患者90例,将其依据麻醉药物的差异进行划分,分为对照组(n=45,丙泊酚麻醉治疗)与观察组(n=45,右美托咪定麻醉治疗),就两组患者的临床麻醉效果、镇痛镇静效果及不良反应发生率展开回顾性分析。 结果 观察组拥有同比对照组明显缩短的麻醉效果(P<0.05);观察组患者的镇痛镇静效果远高于对照组(P<0.05);观察组的不良反应发生率同比对照组数据明显更低(P<0.05),以上所有差异均有统计学意义。结论 施以药物右美托咪定进行无痛胃镜检查,不仅拥有更好的临床麻醉效果,患者不良反应发生率大幅降低,检查、苏醒等时间均明显减少,确保了手术的顺利进行,兼具有效性与安全性,值得临床借鉴并推广。
英文摘要:
      [Abstract] Objective To investigate the clinical efficacies of dexmedetomidine and anesthetic applied in painless gastroscope. Methods A total of 90 patients undergoing painless gastroscopy were enrolled in Third People's Hospital of Huizhou City from January 2018 to January 2020, and they were divided into the control group (n=45, anesthetic with propofol) and the observation group (n=45, anesthetic with dexmedetomidine) according to the difference of anesthetic drugs. The clinical anesthetic efficacy, analgesic sedative efficacy and incidence of adverse reactions (ADRs) of the two groups of patients were analyzed retrospectively. Results The anesthetic efficacy of the observation group was significantly shorter than that of the control group (P < 0.05). The analgesic and sedative efficacies of patients in the observation group were much higher than those in the control group (P < 0.05). The incidence of ADRs in the observation group was significantly lower than that in the control group (P < 0.05). Meanwhile, all the above differences were statistically significant (P < 0.05). Conclusion Applying painless gastroscopy with dexmedetomidine not only has better clinical anesthetic efficacy, but also greatly reduces the incidence of ADRs, and obviously decreases the time of examination and waking, which ensures the smooth operation, is both effective and safe, and is worthy of clinical reference and promotion.
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