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刘明扬1,麻京豫2▲,宋朝功3.绝经及血清GLU、FIB、CRP水平与颈动脉粥样硬化斑块的相关性研究[J].中国医药科学,2020,(1):287-289        基金项目:河南省高等学校重点科研项目(19A320024)
绝经及血清GLU、FIB、CRP水平与颈动脉粥样硬化斑块的相关性研究
Correlation between menopausal, serum GLU, FIB, CRP levels and carotid atherosclerotic plaque
  
DOI:
中文关键词:  颈动脉粥样硬化;绝经;FIB;GLU;CRP
英文关键词:Carotid atherosclerosis; Menopause; FIB; GLU; CRP
作者单位
刘明扬1,麻京豫2▲,宋朝功3 1. 河南中医药大学,河南郑州 450000;2. 河南中医药大学第一临床医学院,河南郑州 450000;3. 河南推拿职业学院,河南洛阳 471000 
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中文摘要:
      [摘要] 目的 探讨女性绝经对其颈动脉粥样硬化的影响,以及体内血清血糖(GLU)、血浆纤维蛋白原(FIB)、血清 C 反应蛋白(CRP)水平与其颈动脉粥样硬化的相关性。方法 选择于 2016 年 1 月~ 2019 年 2 月河南中医药大学第一附属医院心内科及脑病科住院治疗的 40 ~ 60 岁女性患者 232 例,分为已绝经组和未绝经组,比较两组患者颈动脉粥样硬化情况;检查颈部动脉粥样硬化斑块情况,将所有患者分为斑块组和非斑块组,比较其血清 GLU、FIB、CRP 水平。结果 (1)绝经与颈动脉粥样硬化斑块形成呈正相关(P < 0.05);(2)颈动脉粥样硬化斑块患者较非颈动脉粥样硬化斑块患者血清 GLU、FIB、CRP 水平均升高(P < 0.05)。结论 绝经可加快女性颈动脉粥样硬斑块进展,同时,血清 GLU、FIB、CRP 水平与女性颈动脉粥样硬化斑块进展成正相关。
英文摘要:
      [Abstract] Objective To investigate the effects of female menopause on carotid atherosclerosis and the correlation between the levels of GLU, FIB,CRP and carotid atherosclerosis. Methods From January 2016 to February 2019, 232 female patients aged 40-60 who were hospitalized in the Department of Cardiology and Encephalopathy of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine were selected as the study objects.. The patients were divided into the menopausal group and the non-menopausal group. The carotid atherosclerosis was compared between the two groups. All the patients were divided into plaque group and non-plaque group according to the examination of atherosclerotic plaque in the neck. The serum blood glucose (GLU), plasma fibrinogen (FIB), and serum c-reactive protein (CRP) levels were detected and compared. Results (1) There was a positive correlation between menopause and carotid atherosclerotic plaque formation (P < 0.05). (2) Serum GLU, FIB and CRP levels were all increased in patients with carotid atherosclerotic plaque compared with patients without carotid atherosclerotic plaque (P < 0.05). Conclusion Menopause can accelerate the progression of atherosclerotic plaques in women’s carotid arteries. Meanwhile, the serum levels of GLU, FIB and CRP are positively correlated with the progression of atherosclerotic plaques in women’s carotid arteries.
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