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薛峰,杨杰文,朱立柏,陈海钦,阳建平.无创双水平气道正压通气治疗急性左心衰的临床研究[J].中国医药科学,2020,(1):272-274        基金项目:
无创双水平气道正压通气治疗急性左心衰的临床研究
Clinical study on non-nvasive bi-level positive airway pressure ventilation in treatment of acute left heart failure
  
DOI:
中文关键词:  无创双水平气道正压通气;急性左心衰竭;血气指标;心功能;生命体征指标
英文关键词:Non-invasive bi-level positive airway pressure ventilation;Acute left heart failure;Blood gas index;Cardiac function;Vital signs
作者单位
薛峰,杨杰文,朱立柏,陈海钦,阳建平 广东省东莞市塘厦医院,广东东莞 523726 
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中文摘要:
      [摘要] 目的 探讨无创双水平气道正压通气治疗急性左心衰的临床疗效。 方法 选取 2015 年 9 月~ 2018年 9 月我院急诊科收治的 30 例急性左心衰患者为研究对象,根据患者入院时间先后顺序进行分组,包括对照组 15 例及观察组 15 例。两组患者均行常规药物治疗,基于此对照组患者开展吸氧疗法,观察组患者行无创双水平气道正压通气治疗,比较两组患者治疗前后心率、呼吸频率、血气指标、左室射血分数(LVEF)、N末端心房利钠肽原(NT-proBNP)、pH 值及血氧饱和度(SaO2)等指标变化。 结果 治疗前两组患者心率、呼吸频率、血气指标、LVEF、NT-proBNP、pH 值及 SaO2 差异无统计学意义(P > 0.05);治疗后观察组患者心率、呼吸频率、二氧化碳分压(PaCO2)、NT-proBNP 水平低于对照组,SaO2、氧分压(PaO2)、pH 值、LVEF 显著高于对照组,差异有统计学意义(P < 0.05)。 结论 无创双水平气道正压通气治疗急性左心衰可有效改善患者血气指标、心功能、呼吸及心率等多种不良情况,对患者的康复具有积极影响,因此该种治疗方法值得在临床中进行推广应用。
英文摘要:
      [Abstract] Objective To explore the clinical curative effect of non-invasive bi-level positive airway pressure ventilation in treatment of acute left heart failure. Methods 30 patients with acute left heart failure who were admitted to the emergency department of our hospital from September 2015 to September 2018 were selected as research objects.They were divided into the control group(15 cases)and the observation group(15 cases)according to the time of admission.Patients in two groups were treated with routine drug therapy.On basis of it,the control group was treated with oxygen inhalation therapy while the observation group was treated with non-invasive bilevel positive airway pressure ventilation.The changes of heart rate,respiratory rate,blood gas index,left ventricular ejection fraction(LVEF),N-terminal atrial natriuretic peptide(NT-proBNP),pH value and oxygen saturation(SaO2 )of two groups were compared before and after treatment. Results Before treatment, there was no statistically significant difference in heart rate,respiratory rate,blood gas index,LVEF,NT-proBNP,pH value and SaO2 between the two groups(P > 0.05).After treatment,the heart rate,respiratory rate,partial pressure of carbon dioxide(PaCO2),NT-proBNP level in the observation group were lower than those in the control group,while the levels of SaO2 ,partial pressure of oxygen(PaO2),pH value and LVEF in the observation group were significantly higher than those in the control group.The difference was statistically significant(P < 0.05). Conclusion Non-invasive bi-level positive airway pressure ventilation in the treatment of acute left heart failure can effectively improve the blood gas index,cardiac function,respiration and heart rate,which has a positive effect on the rehabilitation of patients.Therefore,this treatment method is worth promoting and applying in clinical practice.
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关键词: 中国医药科学 中国医学 中国医学科学 中华医学 医学杂志 临床医学杂志 医学期刊 中国预防医学 中华预防医学 预防医学杂志 中国药学 药学杂志
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