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刘成杰,张伟波,梁舒镇.基层医院如何规范使用强的松治疗变应性咳嗽的临床探讨[J].中国医药科学,2020,(1):269-271        基金项目:
基层医院如何规范使用强的松治疗变应性咳嗽的临床探讨
Clinical exploration on how to standardize the use of prednisone in treatment of allergic cough in primary hospitals
  
DOI:
中文关键词:  基层医院;强的松;变异性咳嗽;临床效果
英文关键词:Primary hospital;Prednisone;Allergic cough;Clinical curative effect
作者单位
刘成杰,张伟波,梁舒镇 广东省佛山市禅城区中心医院急诊科,广东佛山 528031 
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中文摘要:
      [摘要] 目的 对基层医院规范使用强的松治疗变异性咳嗽的临床效果进行分析。 方法 将 2014 年 1 月~ 2018年 12 月我院收治 76 例变异性咳嗽患者作为本研究对象,随机分为对照组与实验组,对照组使用常规药物进行治疗,实验组使用强的松进行治疗,比较两组患者治疗效果。 结果 (1)对照组与实验组患者短期内治疗总有效率(57.8% vs 89.3%)比较,差异有统计学意义(P < 0.05)。(2)治疗前两组患者嗜酸性粒细胞数、血清 IgE 水平比较差异无统计学意义(P > 0.05),治疗后两组患者嗜酸性粒细胞数、血清 IgE 水平比较差异有统计学意义(P < 0.05)。(3)对照组与实验组患者总不良反应发生率(28.9% vs 7.8%)比较,差异有统计学意义(P < 0.05)。 结论 在基层医院中使用强的松治疗变异性咳嗽的短期疗效较为理想,降低了嗜酸性粒细胞数、血清 IgE 水平,且具有较高的安全性,值得推广使用。
英文摘要:
      [Abstract] Objective To analyze clinical curative effects of standardized use of prednisone in treatment of allergic cough in primary hospitals. Methods From January 2014 to December 2018,76 patients with allergic cough who were admitted and treated in our hospital were selected as research objects.They were randomly divided into the control group and the experimental group.The control group was treated with conventional drugs while the experimental group was treated with prednisone.Curative effects of two groups were compared. Results (1)The total short-term effective rate in the control group and the experimental group(57.8% vs 89.3%)were statistically significantly different(P< 0.05).(2)There was no statistically significant difference in eosinophil count and serum IgE level between the two groups before treatment(P > 0.05).After treatment,there were statistically significant differences in eosinophil count and serum IgE level between the two groups(P < 0.05).(3)The incidence of total adverse reactions in the control group and the experimental group(28.9% vs 7.8%)were statistically significantly different(P < 0.05). Conclusion The shortterm curative effects of prednisone in treating allergic cough in primary hospitals is ideal.It can reduce eosinophils count and serum IgE level.It has higher safety,which is worthy of promotion and application.
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