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杨建伟,蔡海东▲.右美托咪定预防剖宫产术中仰卧位低血压综合征的临床观察[J].中国医药科学,2020,(1):222-224        基金项目:
右美托咪定预防剖宫产术中仰卧位低血压综合征的临床观察
Clinical observation of dexmedetomidine in preventing supine hypotension syndrome during cesarean section
  
DOI:
中文关键词:  右美托咪定:剖宫产;仰卧位低血压综合征;新生儿窒息
英文关键词:Dexmedetomidine;Cesarean section;Supine hypotension syndrome;Neonatal asphyxia
作者单位
杨建伟,蔡海东▲ 湖北省阳新县妇幼保健院麻醉科,湖北阳新 435200 
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中文摘要:
      [摘要] 目的 观察右美托咪定对预防剖宫产术中仰卧位低血压综合征发生的临床疗效。 方法 选取本院2018 年 3 月~ 2019 年 6 月 ASA Ⅰ~Ⅱ级行 300 例剖宫产术的初产妇,将其随机分为对照组 150 例(微量推注泵静脉推注生理盐水 10mL)和观察组 150 例(微量推注泵静脉推注配制 20μg 右美托咪定稀释至10mL)。观察两组患者麻醉操作结束后仰卧位低血压综合征发生率及新生儿娩出 1、5、10min Apgar 评分情况。 结果 实验组仰卧位低血压综合征发生率明显低于对照组(P < 0.05),两组患者新生儿娩出 1、5、10min Apgar 评分比较差异无统计学意义(P > 0.05)。 结论 右美托咪定能够有效降低剖宫产术中仰卧位低血压综合征的发生率,且不引起新生儿窒息。
英文摘要:
      [Abstract] Objective To observe the clinical effect of dexmedetomidine on the prevention of supine hypotension syndrome during cesarean section. Methods A total of 300 primiparous women undergoing cesarean section in ASA Ⅰ - Ⅱ grade between March 2018 and June 2019 in our hospital were randomly divided into control group and observation group,with 150 cases in each group.The control group was given intravenous bolus injection of 10 mL saline;while the observation group was given 20 μg dexmedetomidine diluted to 10 mL by intravenous bolus injection.The incidence of supine hypotension syndrome and Apgar scores at 1,5 and 10 minutes after delivery were observed in the two groups after the completion of anesthesia. Results The incidence of supine hypotension syndrome in the observation group was significantly lower than that in the control group (P < 0.05),and there was no significant difference in Apgar scores between the two groups at 1,5,10 minutes (P > 0.05). Conclusion Dexmedetomidine can effectively reduce the incidence of supine hypotension syndrome during cesarean section and does not cause neonatal asphyxia.
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