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胡海洋,陈明刚,杨业永,张雪芹.微生物形态学检验用于感染性疾病诊断的应用价值[J].中国医药科学,2020,(1):216-218        基金项目:
微生物形态学检验用于感染性疾病诊断的应用价值
Application value of microbial morphology test for diagnosis of infectious diseases
  
DOI:
中文关键词:  感染性疾病;微生物形态学;病原菌;免疫;临床诊断;应用价值
英文关键词:Infectious diseases;Microbial morphology;Pathogenic bacteria;Immunity;Clinical diagnosis;Application value
作者单位
胡海洋,陈明刚,杨业永,张雪芹 湖北省钟祥市人民医院检验科,湖北钟祥 431900 
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中文摘要:
      [摘要] 目的 探讨微生物形态学检验在感染性疾病的临床诊断中的应用价值。 方法 收集我院 2016 年 1月~ 2017 年 12 月感染性疾病的 120 例患者作为研究对象,将其体内分离出的 120 株肺炎链球菌分为研究组与对照组,各 60 株病原菌。对照组病原菌不给予任何处理措施,临床医师依据患者的检验进行给予相应的药物处理。研究组患者检测出的病原菌进行微生物形态学的检验,应用药敏测试的方法对患者的感染性疾病进行控制与治疗,观察两组患者病原菌感染情况及程度。 结果 研究组病原菌株轻度感染率为 76.67%、中度感染率为 20.00%、重度感染率为 3.33%,对照组病原菌株轻度感染率为 41.67%、中度感染率为36.67%、重度感染率为 21.67%,研究组病原菌株感染程度显著轻于对照组,差异有统计学意义(P < 0.05)。研究组患者免疫功能下降率为 11.67%,显著低于对照组的 41.67%,差异有统计学意义(P < 0.05)。 结论 临床中对于感染性疾病采取微生物形态学检验是可行的,能够及时了解患者感染情况,在病原菌传播与监测上具有重要的应用价值,值得临床中推广应用。
英文摘要:
      [Abstract] Objective To explore the application value of microbial morphology test in the clinical diagnosis of infectious diseases. Methods 120 patients with infectious diseases admitted to our hospital from January 2016 to December 2017 were selected.The 120 strains of Streptococcus pneumoniae isolated from the patients were divided into study group and control group,60 strains of pathogens in each group.No treatment measures were taken for the pathogens detected in the control group,and the clinician gave corresponding drug treatment according to the patient’s test.The pathogens detected by the patients in the study group were tested for microbial morphology,and the drug-sensitive test method was used to control and treat the infectious diseases of these patients.The pathogen infection status and degree of the two groups were observed. Results Among the pathogenic strains in the study group,76.67% were mild infections,20.00% were moderate infections,and 3.33% were severe infections.Among the pathogenic strains in the control group,41.67% were mild infections,36.67% were moderate infections,and 21.67% were severe infections.The degree of infection of the pathogenic strains in the study group was significantly lower than that in the control group,and the difference between the two groups was statistically significant (P < 0.05).The immune function decline rate of the study group was 11.67%,which was significantly lower than that of the control group (41.67%),and the difference between the groups was also statistically significant (P < 0.05). Conclusion It is feasible to adopt microbial morphological examination for infectious diseases in clinical practice.Which helps to understand the infection status of patients in time and has important application value in the transmission and monitoring of pathogenic bacteria.Therefore,it is worthy of popularization and application in clinical practice.
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