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林瑞峰,陈瑞容,温春霞,关玉云,何栋.甲型流感患儿尤其是重症患儿血清铁蛋白水平变化的临床意义分析[J].中国医药科学,2020,(1):126-128        基金项目:广东省阳江市医疗卫生类科技计划项目(社发【2018】34)
甲型流感患儿尤其是重症患儿血清铁蛋白水平变化的临床意义分析
Analysis on clinical significance of changes of serum ferritin levels in children with influenza A, especially in critically ill children
  
DOI:
中文关键词:  血清铁蛋白;七项呼吸道病毒检测;准确价值;效果分析
英文关键词:Serum ferritin; Seven respiratory virus tests; Accurate value; Effect analysis
作者单位
林瑞峰,陈瑞容,温春霞,关玉云,何栋 广东省阳江市人民医院,广东阳江 529500 
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中文摘要:
      [摘要] 目的 分析甲型流感患儿尤其是重症患儿血清铁蛋白水平变化的临床意义。 方法 选取我院 2016 年8 月~ 2018 年 8 月,本科收治的患儿 80 例,患儿入院后抽取静脉血 2mL 予以血清铁蛋白指标检测,同时予以呼吸道病毒七项检查,呼吸道七项病毒检查结果记录后,分析四个组别间的血清铁蛋白指标。 结果 选取80 例流感样病例,甲型流感病毒阳性 71 例,甲型流感病毒阴性 9 例,其中甲型流感阳性组患儿中,62 例危重症,9 例普通型。对所有患儿予以全身检查。9 例阴性患儿血清铁蛋白水平为(350.50±15.30)ng/mL,71例血清铁蛋白水平为(473.63±16.30)ng/mL、其中普通型患儿血清铁蛋白水平为(427.00±18.30)ng/mL,危重型患儿血清铁蛋白水平为(1061.50±71.40)ng/mL,四组血清铁蛋白水平,两组分别比较,差异有统计学意义,其中阴性组<阳性组(t=21.480,P=0.000);普通型组<危重组(t=26.382,P=0.000)。 结论 血清铁蛋白在甲型流感患儿尤其是危重患儿早期诊断的价值显著,可以成为流感样病例患儿入院后的常规检查,在流行季节,有利于危重型流感的早期诊断和治疗,降低并发症,提升患儿生活水平。
英文摘要:
      [Abstract] Objective To analyze clinical significance of changes of serum ferritin levels in children with influenza A, especially in critically ill children. Methods 80 children who were admitted to our department from August 2016 to August 2018 were selected. After admission, 2mL of venous blood was extracted for serum ferritin test. At the same time, seven respiratory virus tests were performed, and the results of seven respiratory virus tests were recorded. Then, serum ferritin indexes were analyzed among the four groups. Results 80 influenza-like cases were selected. Among which, 71 cases were positive for influenza A virus and 9 cases were negative for influenza A virus. Among the children with influenza A positive, 62 were critically ill and 9 were common. A full body examination was performed on all children. Serum ferritin levels were (350.50±15.30) ng/mL in 9 children with negative influenza A virus and (473.63±16.30) ng/mL in 71children with positive influenza A virus. Among them, the serum ferritin level of common children was ( 427.00±18.30) ng/mL and the serum ferritin level of critically ill children was (1061.50±71.40) ng/mL. The serum ferritin levels of the four groups were statistically significant by comparison between the two groups. The serum ferritin level of the negative group was lower than that of the positive group (t=21.480, P=0.000). The serum ferritin level of the common group was lower than that of the critical ill group (t=26.382, P=0.000). Conclusion Serum ferritin has a significant value in early diagnosis of children with influenza A, especially in critically ill children and which can be used as a routine examination for children with influenzalike cases after admission. In the epidemic season, it is beneficial to the early diagnosis and treatment of severe influenza, reduce complications and improve the living standards of children.
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