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蔡方梅,王琦,曾红英.不同剂量达克罗宁对患者胃镜检查效果的影响[J].中国医药科学,2020,(1):95-97        基金项目:
不同剂量达克罗宁对患者胃镜检查效果的影响
Exploration on effects of different doses of dyclonine on the effect of gastroscopy for patients
  
DOI:
中文关键词:  胃镜检查;达克罗宁;不同剂量;满意度
英文关键词:Gastroscopy; Dyclonine; Different doses; Satisfaction
作者单位
蔡方梅,王琦,曾红英 广东省东莞市樟木头医院,广东东莞 523620 
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中文摘要:
      [摘要] 目的 探讨不同剂量达克罗宁对患者胃镜检查效果的临床影响。 方法 将 2018 年 10 月~ 2019 年 4月来我院接受胃镜检查的 1480 例患者作为研究对象,采用随机数字表法分为对照组(达克罗宁剂量:8mL)和观察组(达克罗宁剂量:10mL),每组 740 例,对每位患者行胃镜检查前 30 分钟内口服达克罗宁药物,按照以上比例。对比不同剂量达克罗宁药物与黏膜可视度的相关性、胃镜检查时间、操作满意度、胃镜检查下患者上消化道病变检出情况等。结果 达克罗宁 10mL 组患者的胃镜检查时间、操作满意度显著优于达克罗宁 8mL 组;达克罗宁 10mL 组泡沫粘附明显减少,黏膜可视度显著增加,优于达克罗宁 8mL 组,证明达克罗宁剂量与黏膜可视度呈正相关;达克罗宁 10mL 组患者的消化道病变情况显著少于达克罗宁 8mL 组,差异均有统计学意义(P < 0.05)。 结论 对接受胃镜检查的患者行检查前口服达克罗宁药物,可有效的缩短检查时间,提高操作满意度,同时还能提高镜下黏膜可视度,达克罗宁剂量越大临床效果越好,结合临床效果和经济指标推荐使用剂量为 10mL 的达克罗宁药物。
英文摘要:
      [Abstract] Objective To explore clinical effects of different doses of dyclonine on the effect of gastroscopy for patients.Methods 140 patients who underwent gastroscopy in our hospital from October 2018 to April 2019 were selected as research objects. According to the random number table method, they were divided into the control group (dosage of dyclonine: 8mL) and the observation group (dosage of dyclonine: 10mL), with 740 cases in each group. Patients in two groups were all given d dyclonine orally within 30 minutes before gastroscopy according to the above ratio. The correlation between different doses of dyclonine and mucosa visibility, gastroscopy time, operation satisfaction and detection of upper gastrointestinal lesions under gastroscopy were compared between two groups. Results The gastroscopy time and operational satisfaction of patients in the dyclonine 10mL group were significantly better than the dyclonine 8mL group. The foam adhesion of dyclonine 10mL group was significantly reduced and mucosal visibility increased significantly, which were better than those in dyclonine 8mL group, demonstrating that dyclonine dose was positively correlated with mucosal visibility. The gastrointestinal lesions of the dyclonine 10mL group were significantly less than those of the dyclonine 8mL group, and the differences were statistically significant (P < 0.05). Conclusion Oral administration of dyclonine for patients undergoing gastroscopy can effectively shorten the examination time, improve the operation satisfaction and improve the microscopic mucosal visibility. The greater the dose of dyclonine, the better the clinical effect. A dose of 10mL of dyclonine is recommended in combination with clinical effects and economic indexes.
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