中国医药科学杂志欢迎您.   今天是:        
石帆,邱基庆,陈明毅,黎亿强.低剂量苯巴比妥治疗轻度胃肠炎伴婴幼儿良性惊厥对惊厥表现的影响[J].中国医药科学,2020,(1):92-94        基金项目:
低剂量苯巴比妥治疗轻度胃肠炎伴婴幼儿良性惊厥对惊厥表现的影响
Effects of low dose phenobarbital in treatment of benign infantile convulsions with mild gastroenteritis on convulsions symptoms
  
DOI:
中文关键词:  苯巴比妥;婴幼儿;轻度胃肠炎伴婴幼儿良性惊厥;惊厥
英文关键词:Phenobarbital; Infants; Benign infantile convulsions with mild gastroenteritis; Convulsions
作者单位
石帆,邱基庆,陈明毅,黎亿强 广东省佛山市高明区人民医院儿科,广东佛山 528500 
摘要点击次数: 350
全文下载次数: 664
中文摘要:
      [摘要] 目的 探讨低剂量苯巴比妥治疗轻度胃肠炎伴婴幼儿良性惊厥(BICG)对惊厥表现的影响。方法 选取 2017 年 1 月~ 2018 年 12 月我院新诊断 BICG 患儿 100 例,按随机数字表法分为观察组和对照组,每组50 例。对照组给予综合疗法治疗,观察组在此基础上给予低剂量苯巴比妥治疗。比较两组有效性和安全性的评价指标。结果 观察组再次发作、全面性发作的发生率显著低于对照组,观察组总惊厥时间、总惊厥次数显著低于对照组,差异具有统计学意义(P< 0.05)。两组不良反应发生率比较,差异无统计学意义(P> 0.05)。结论 与单纯综合疗法比较,在此基础上联用低剂量苯巴比妥可改善 BICG 的惊厥表现,且不增加不良反应或不良事件。
英文摘要:
      [Abstract] Objective To explore the effect of low dose phenobarbital in treatment of benign infantile convulsions with mild gastroenteritis on convulsions symptoms. Methods One hundred children who were newly diagnosed as BICG in our hospital from January 2017 to December 2018 were selected. According to the random number table method, they were divided into the observation group and the control group, with 50 cases in each group. The control group was treated with comprehensive therapy while the observation group was treated with low dose phenobarbital on this basis. Evaluation indexes of effectiveness and safety were compared between two groups. Results Incidence of relapse and generalized seizure of the observation group was significantly lower than that of the control group. The total convulsion time and frequency of convulsions of the observation group were significantly lower than those of the control group. The difference was statistically significant (P < 0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion Compared with the simple comprehensive therapy, the combination of low dose phenobarbital on this basis can improve the convulsion symptoms of BICG without increasing adverse reactions or adverse events.
查看全文  查看/发表评论  下载PDF阅读器
关闭
关键词: 中国医药科学 中国医学 中国医学科学 中华医学 医学杂志 临床医学杂志 医学期刊 中国预防医学 中华预防医学 预防医学杂志 中国药学 药学杂志
药理杂志 中国中医 中医杂志 中华中医药 中医药杂志 中国医疗 医疗器械杂志 中国中西医结合 中国医药 医药杂志 医药期刊 医药论文 医学论文 科研论文 职称论文
function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=970261AF74811A5D673BCD6251A9EA6BE1B9779CF0C07BEB054742F4DC222A9C60D6BD62EC31C97966EFBF56EE1A597405E0293EB73F03EDB3598D3544D691053CA9E980C7AF28245A42A81DCFADE75E0488F9E3F4039AAEE1855EA585ECECB2F726A1EBEC7B0C0D27BC8A409EFD65477ED39C8BD8BC7D18B3F0D576792FF878739CCED13E0BFB3A&pcid=&cid=&jid=&yid=0D1D160AB8016934&aid=&vid=&iid=CA4FD0336C81A37A&sid=08805F9252973BA4&eid=BB0EA31DB1B01173&fileno=20200027&flag=1&is_more=0">