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孙亮.布地奈德联合特布他林雾化吸入治疗小儿喘息性支气管炎的疗效[J].中国医药科学,2020,(1):89-91        基金项目:
布地奈德联合特布他林雾化吸入治疗小儿喘息性支气管炎的疗效
Curative effects of budesonide combined with terbutaline atomization inhalation in treatment of asthmatic bronchitis in children
  
DOI:
中文关键词:  布地奈德;特布他林;雾化吸入;小儿喘息性支气管炎;临床疗效
英文关键词:Budesonide; Terbutaline; Aerosol inhalation; Asthmatic bronchitis in children; Clinical curative effects
作者单位
孙亮 广东省东莞市第五人民医院,广东东莞 523000 
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中文摘要:
      [摘要] 目的 探讨布地奈德联合特布他林雾化吸入治疗小儿喘息性支气管炎的疗效。方法 选取 2018 年1 ~ 12 月在我院接受治疗的 51 例喘息性支气管炎患儿作为研究对象,采用随机数字表法分组。两组患儿均给予常规对症治疗,对照组(n=25)采用地塞米松治疗,观察组(n=26)采用布地奈德联合特布他林雾化吸入治疗,比较两组的临床疗效、症状消失时间和用药安全性。结果 两种用药方案的有效性比较,观察组的治疗有效率明显高于对照组,差异有统计学意义(P < 0.05);两组患儿的症状缓解情况比较,观察组患儿咳嗽、肺部湿啰音、发热、气促等症状的消失时间和住院时间均明显短于对照组,差异有统计学意义(P < 0.05);两种治疗方案的安全性比较,两组的不良反应发生率差异无统计学意义(P > 0.05)。结论 在小儿喘息性支气管炎的临床治疗上,采用布地奈德联合特布他林雾化吸入治疗兼具有效性和安全性,可缩短患儿的各项症状缓解时间,值得进一步推广和应用。
英文摘要:
      [Abstract]Objective To explore curative effects of budesonide combined with terbutaline atomization inhalation in treatment of asthmatic bronchitis in children. Methods 51 children with asthmatic bronchitis who were treated in our hospital from January 2018 to December 2018 were selected as main research objects. According to the random number table method, they wer divided into two groups. Patients in both groups were given conventional symptomatic treatment. The control group (n=25) was treated with dexamethasone while the observation group (n=26) was treated with budesonide combined with terbutaline inhalation. The clinical curative effects, disappearance time of symptoms and drug safety of two groups were compared between two groups. Results After comparing the effectiveness of the two regimens, the effective rate of treatment of the observation group was significantly higher than that of the control group. There was a significant difference between the two groups(P < 0.05). After comparing the remission of symptoms of two groups, the disappearance time of symptoms such as cough, pulmonary rales, fever and shortness of breath and hospital stay of the observation group were all significantly shorter than those of the control group. There were significant differences between the two groups (P < 0.05). After comparing the safety of the two treatment regimens, there was no significant difference in incidence of adverse reactions between two groups (P > 0.05). Conclusion In clinical treatment of asthmatic bronchitis in children, budesonide combined with terbutaline inhalation therapy has both effectiveness and safety, which can shorten the symptom relief time of children. It is worthy of further promotion and application.
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