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曲柏强,蔡高翔.HRCT及定量CT对慢性阻塞性肺疾病早期诊断价值的研究[J].中国医药科学,2019,(16):222-224        基金项目:浙江省温岭市科技计划项目
HRCT及定量CT对慢性阻塞性肺疾病早期诊断价值的研究
Value of HRCT and quantitative CT in early diagnosis of chronic obstructive pulmonary disease
  
DOI:
中文关键词:  慢性阻塞性肺疾病;肺功能检查;高分辨率 CT;肺容积;肺密度
英文关键词:Chronic obstructive pulmonary disease;Pulmonary function examination;High resolution CT;Lung volume;Lung density
作者单位
曲柏强,蔡高翔 浙江省温岭市中医院,浙江温岭 317500 
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中文摘要:
      [摘要] 目的 探讨 HRCT 及定量 CT 对慢性阻塞性肺疾病(COPD)早期诊断价值。 方法 收集 2016 年 8月~ 2017 年 10 月浙江温岭市中医院呼吸内科收治的 COPD 患者 100 例为观察组,另健康体检者 60 例为对照组,所有研究对象均接受肺通气功能检查。观察组入院 3 天内行 HRCT 容积扫描,图像传输至工作站,记录肺容积、肺密度各项参数。 结果 观察组 FEV1、FVC、FEV1/FVC、FEV1% 明显低于对照组,RV/TLC 明显高于对照组,差异有统计学意义(P < 0.05)。与 COPD Ⅰ级患者比较,COPD Ⅱ级患者深吸气末肺密度和深呼气末肺密度明显变深,Vin、TEV 及 EI 明显升高,差异有统计学意义(P < 0.05);Ⅰ级与Ⅱ级患者 Vex和 TLV 比较,差异无统计学意义(P > 0.05)。 结论 HRCT 及定量 CT 对早期 COPD 有较好的诊断价值,可鉴别诊断 COPD Ⅰ级与Ⅱ级,对评定早期 COPD 患者有重要价值。
英文摘要:
      [Abstract] Objective To explore the value of HRCT and quantitative CT in early diagnosis of chronic obstructive pulmonary disease (COPD). Methods 100 COPD patients admitted to Department of Respiratory Medicine of Wenling Hospital of Traditional Chinese Medicine in Zhejiang Province from August 2016 to October 2017 were selected as the observation group,and 60 healthy people as the control group.All the subjects were examined for pulmonary ventilation function.The observation group was given HRCT volume scan within 3 days after admission,and the image was transmitted to the workstation to record the parameters of lung volume and lung density. Results FEV1,FVC,FEV1/FVC and FEV1% in the observation group were significantly lower than those in the control group,and RV/TLC was significantly higher than those in the control group,with statistical significance (P < 0.05). Compared with COPD grade Ⅰ patients,COPD grade Ⅱ patients had significantly deeper end-inspiratory lung density and higher end-expiratory lung density,Vin,TEV and EI (P < 0.05).There was no significant difference between COPD grade Ⅰ patients and COPD grade Ⅱ patients in Vex and TLV (P > 0.05). Conclusion HRCT and quantitative CT have better diagnostic value for early COPD.They can differentiate COPD grade Ⅰ from grade Ⅱ and have important value for evaluating early COPD patients.
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