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李燕,吴玉梅,万彬,崔静.灌注指数在极早产儿动脉导管未闭诊断中的临床意义[J].中国医药科学,2019,(16):103-106        基金项目:滨州医学院科研计划与科研启动基金项目 (BY2016KJ02)
灌注指数在极早产儿动脉导管未闭诊断中的临床意义
Clinical significance of perfusion index in diagnosis of patent ductus arteriosus in very premature infants
  
DOI:
中文关键词:  极早产儿;动脉导管未闭;灌注指数;脉搏血氧测定法;经皮血氧饱和度
英文关键词:Very premature infants;Patent ductus arteriosus;Perfusion index;Pulse oximetry;Percutaneous oxygen saturation
作者单位
李燕,吴玉梅,万彬,崔静 滨州医学院附属医院新生儿科,山东滨州 256603 
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中文摘要:
      [摘要] 目的 探讨灌注指数(PI 值)和经皮血氧饱和度(SpO2)在极早产儿(28 ~ 32 周)动脉导管未闭诊断中的临床意义。 方法 选取 2017 年 1 月~ 2018 年 5 月我院新生儿收治的 84 例胎龄 28 ~ 32 周早产儿,按生后 5d 的心脏彩超检查分为小型动脉导管未闭组(12 例)、中型动脉导管未闭组(14 例)、大型动脉导管未闭组(12 例)和对照组(46 例)。分别监测各组患儿生后 5d 脉搏血氧监测仪器上 PI 曲线稳定后 6s 内的 PI值和经皮血氧饱和度(SpO2)。比较四组的 PI 值和 SpO2的变化。 结果 对照组的 SpO2分别与小型动脉导管组、中型动脉导管组和大型动脉导管组的 SpO2 比较,差异无统计学意义(P > 0.05)。对于极早产儿的 PI 值,小型动脉导管未闭组与对照组比较,差异无统计学意义(P > 0.05);中型动脉导管未闭组与对照组比较,差异无统计学意义(P > 0.05),大型动脉导管未闭组与对照组比较,差异有统计学意义(P < 0.05)。 结论 经皮血氧饱和度对诊断极早产儿动脉导管未闭无参考意义,极早产儿的 PI 值可对早期诊断极早产儿大型动脉导管未闭提供帮助。
英文摘要:
      [Abstract] Objective To explore the clinical significance of perfusion index(PI)and percutaneous blood oxygen saturation(SpO2)in diagnosis of patent ductus arteriosus in very premature infants(28-32 weeks). Methods 84 premature infants of 28-32 weeks who were admitted and treated in our hospital from January 2017 to May 2018 were selected.According to echocardiography after 5 days of birth,they were divided into the small patent ductus arteriosus group(n=12),medium patent ductus arteriosus group(n=14),large patent ductus arteriosus group(n=12)and the control group(n=46).The PI values and percutaneous oxygen saturation(SpO2)within 6s after stabilization of the PI curve on pulse oximetry instrument after 5 days after birth were monitored.The changes of PI value and SpO2 in the four groups were compared. Results There was no statistically significant difference in SpO2 between the control group and the small patent ductus arteriosus group,medium patent ductus arteriosus group and large patent ductus arteriosus group (P > 0.05).For the PI value of very premature infants,there was no statistically significant difference between the small patent ductus arteriosus group and the control group(P > 0.05).For the PI value of very premature infants,there was no statistically significant difference between the medium patent ductus arteriosus group and the control group(P > 0.05).For the PI value of very premature infants,there were statistically significant differences between the large patent ductus arteriosus group and the control group(P > 0.05). Conclusion Percutaneous oxygen saturation has no reference value in the diagnosis of patent ductus arteriosus in very premature infants.PI values of very premature infants may be helpful for early diagnosis of large patent ductus arteriosus in very premature infants.
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