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陈泽杰.地奈德乳膏联合萘替芬酮康乳膏治疗对面部脂溢性皮炎的效果与安全性[J].中国医药科学,2019,(16):81-83        基金项目:
地奈德乳膏联合萘替芬酮康乳膏治疗对面部脂溢性皮炎的效果与安全性
Curative effects and safety of desonide cream combined with naftifine ketoconazole cream in treatment of facial seborrheic dermatitis
  
DOI:
中文关键词:  地奈德乳膏;萘替芬酮康乳膏;面部脂溢性皮炎;不良反应
英文关键词:Desonide cream; Naftifine ketoconazole cream; Facial seborrheic dermatitis; Adverse reactions
作者单位
陈泽杰 广东省惠来县人民医院,广东惠来 515200 
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中文摘要:
      [摘要] 目的 探究面部脂溢性皮炎患者实施地奈德乳膏与萘替芬酮康乳膏联合治疗的临床效果。方法 择取2017 年 3 月 ~ 2018 年 10 月期间我院收治的面部脂溢性皮炎患者 40 例为研究对象,采取完全随机分组方法将患者分为对照组 20 例及观察组 20 例。对照组患者行地奈德乳膏治疗,观察组患者基于地奈德乳膏行萘替芬酮康唑乳膏治疗。对两组患者治疗前后症状积分以及两组患者不良反应情况进行记录和比较。结果 两组患者治疗前症状积分数据比较,差异无统计学意义(P > 0.05),治疗后两组患者症状积分相比同组治疗前均有明显下降,其中观察组患者下降幅度更多,差异有统计学意义(P < 0.05)。两组不良反应发 生率差异无统计学意义(P > 0.05)。结论 地奈德与萘替芬酮康唑乳膏联合应用对面部脂溢性皮炎疗效确切,安全性高,可用于临床中推广。
英文摘要:
      [Abstract] Objective To study the clinical curative effects of desonide cream combined with naftifine ketoconazole cream in treatment of patients with facial seborrheic dermatitis. Methods Forty patients with facial seborrheic dermatitis who were admitted and treated in our hospital from March 2017 to October 2018 were selected as research objects. According to the completely random grouping method, they were divided into the control group and the observation group, with 20 cases in each group. Patients in the control group were treated with desonide cream while patients in the observation group were treated with naftifine ketoconazole cream based on desonide cream. The symptoms scores before and after treatment and the adverse reactions of patients in the two groups were recorded and compared by statistical software. Results There was no statistically significant difference in the symptom score before treatment between the two groups (P > 0.05). After treatment, the symptom scores of the two groups were significantly lower than those of the same group before treatment. Among them, the patients in the observation group had more declines, and the difference was statistically significant (P < 0.05). There was no statistically significant difference in the incidence of adverse reactions between the two groups (P > 0.05). Conclusion Desonide cream combined with naftifine ketoconazole cream in treatment of patients with facial seborrheic dermatitis has accurate curative effects and high safety, which can be clinically promoted.
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