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李澍.头孢地嗪联合氨溴索治疗中老年患者下呼吸道感染的临床效果观察[J].中国医药科学,2019,(16):63-65        基金项目:
头孢地嗪联合氨溴索治疗中老年患者下呼吸道感染的临床效果观察
Observation on clinical curative effect of cefodizime combined with ambroxol in the treatment of lower respiratory tract infection in middle-aged and elderly psatients
  
DOI:
中文关键词:  头孢地嗪;氨溴索;下呼吸道感染;多种病原体感染
英文关键词:Cefodizime;Ambroxol;Lower respiratory tract infection;Multiple pathogen infection
作者单位
李澍 江苏省中西医结合医院药学部临床药学室,江苏南京 210028 
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中文摘要:
      [摘要] 目的 探讨头孢地嗪联合氨溴索治疗中老年患者下呼吸道感染的临床效果。 方法 选择 2015 年 4 月20 日~ 2018 年 4 月 25 日我院就诊的 45 例中老年患者下呼吸道感染患者作为探究对象,实施信封随机分组模式进行分组,分别 22、23 例,分别实施头孢地嗪联合氨溴索治疗、头孢地嗪治疗,比较两组治疗效果、临床症状缓解时间、不良反应发生情况。 结果 观察组治疗效果为 95.45%(21/22)、咳痰:(4.21±0.54)d、气促:(4.02±1.11)d、肺部啰音:(4.44±1.08)d,优于对照组,P < 0.05,但在不良反应发生率的比较中,两组之间差异无统计学意义(P > 0.05)。 结论 头孢地嗪联合氨溴索治疗中老年患者下呼吸道感染效果较佳。
英文摘要:
      [Abstract] Objective To explore the clinical curative effect of cefodizime combined with ambroxol in the treatment of lower respiratory tract infection in middle-aged and elderly patients. Methods 45 middle-aged and elderly patients with lower respiratory tract infection who were treated in our hospital from April 20,2015 to April 25,2018 were selected as research objects.According to envelope random grouping mode,they were divided into two groups,with 22 cases and 23 cases respectively.They were respectively treated by cefodizime combined with ambroxol and cefodizime.The curative effects,relief time of clinical symptom and occurrence of adverse reactions were compared between the two groups. Results The curative effect,expectoration,shortness of breath and pulmonary rales of the observation group were respectively 95.45%(21/22),(4.21±0.54)d,(4.02±1.11)d and (4.44±1.08) d,better than those of the control group,P < 0.05.However,there was no significant difference between the two groups in the incidence of adverse reactions,P > 0.05. Conclusion Cefodizime combined with ambroxol in treatment of middle-aged and elderly patients with lower respiratory tract infection has better effect.
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