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陆锦源.每日唤醒对ICU慢性阻塞性肺疾病行机械通气患者的影响[J].中国医药科学,2019,(9):194-196        基金项目:广东省佛山市卫生和计生局医学科研课题 (20190238)
每日唤醒对ICU慢性阻塞性肺疾病行机械通气患者的影响
Effect of daily awakening on chronic obstructive pulmonary disease patients undergoing mechanical ventilation in ICU
  
DOI:
中文关键词:  每日唤醒;ICU;慢性阻塞性肺疾病;机械通气
英文关键词:Daily awakening; ICU; Chronic obstructive pulmonary disease; Mechanical ventilation
作者单位
陆锦源 广东省佛山市南海区第四人民医院,广东佛山 528211 
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中文摘要:
      目的 分析每日唤醒对 ICU 慢性阻塞性肺疾病行机械通气患者产生的影响。 方法 此次纳入研究100 例 ICU 慢性阻塞性肺疾病行机械通气患者均为 2014 年 11 月~ 2017 年 11 月收治,参加此次研究患者均给予芬太尼与丙泊酚进行镇痛和镇静,在此基础上以随机分组的形式将其分为两组,对照组 50 例患者不予以唤醒,实验组 50 例患者予以每日唤醒,对其效果进行分析。 结果(1)实验组患者心率、呼吸频率、动脉血氧、动脉二氧化碳分压、平均动脉压均优于对照组患者,差异有统计学意义(P < 0.05);两组患者血氧饱和度指标变化比较并无统计学差异(P > 0.05)。(2)实验组患者停药后完全清醒时间与机械通气时间均较对照组患者短,组间对比数据差异有统计学意义(P < 0.05)。(3)实验组患者停药后不良反应发生率(14.0%)较对照组患者停药后不良反应发生率(34.0%)低,差异有统计学意义(P < 0.05)。 结论 每日唤醒在 ICU 慢性阻塞性肺疾病行机械通气患者中有着重要的意义,可改善患者呼吸循环指标,缩短停药后完全清醒时间,降低停药后不良反应的发生,加速患者的康复,值得在临床中推广应用。
英文摘要:
      Objective To analyze the effect of daily awakening on chronic obstructive pulmonary disease patients undergoing mechanical ventilation in ICU. Methods 100 ICU patients with chronic obstructive pulmonary disease who underwent mechanical ventilation and were admitted and treated from November 2014 to November 2017 were included in the study. All patients who participated in this study were given fentanyl and propofol for analgesia and sedation. On basis of it, they were divided into two groups. 50 patients in the control group were not given daily awakening while 50 patients in the experimental group were given daily awakening. Effects were analyzed. Results (1)The heart rate, respiratory rate, arterial blood oxygenation, arterial carbon dioxide partial pressure and mean arterial pressure in the experimental group were better than those in the control group. The difference between the groups was significant (P < 0.05). There was no difference in the changes of blood oxygen saturation indexes between the two groups (P > 0.05). (2)The time of complete awake and mechanical ventilation after drug withdrawal in the experimental group were shorter than those in the control group, and the difference between the groups was significant (P < 0.05). (3)The incidence of adverse reactions after drug withdrawal in the experimental group was 14.0%, lower than that in the control group 34.0%. The difference between the groups was significant (P < 0.05). Conclusion Daily awakening has important significance in chronic obstructive pulmonary disease patients undergoing mechanical ventilation in ICU. It can improve the respiratory circulation index of patients, shorten the total waking time after drug withdrawal, reduce the occurrence of adverse reaction and accelerate the recovery of patients, which is worthy of clinical promotion and application.
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