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杨军华.普拉克索治疗帕金森病的安全性与有效性评价[J].中国医药科学,2018,(3):73-75        基金项目:
普拉克索治疗帕金森病的安全性与有效性评价
Evaluation of the safety and efficacy of Praxol in the treatment of Parkinson's disease
  
DOI:
中文关键词:  普拉克索;帕金森病;安全性;有效性
英文关键词:Pramipexole;Parkinson's disease;Safety;Efficacy
作者单位
杨军华 河南省开封市中心医院神经内科 
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中文摘要:
      目的 探讨普拉克索治疗帕金森病的安全性和有效性。 方法 选取 2015 年 5 月~ 2016 年 5 月我院收治的帕金森患者作为研究对象,随机分为观察组和对照组,各 65 例,两组患者均在常规治疗的基础上予以治疗,观察组使用普拉克索,对照组使用溴隐亭。 结果 经治疗后,观察组与对照组在“开、关”时间,生活活动、精神情绪、运动检查、并发症方面的得分均显著提高(P < 0.05),观察组有效率显著高于对照组(83.08% vs 69.23%,P < 0.05),在并发症方面,观察组患者头晕例数显著少于对照组(P < 0.05)。 结论 普拉克索对帕金森的治疗具有较好的疗效,安全性好,临床价值较高,值得进一步研究和推广。
英文摘要:
      Objective To explore the safety and efficacy of Praxol in the treatment of Parkinson's disease. Methods One hundred and thirty patients with Parkinson's disease admitted in our hospital from May 2015 to May 2016 were randomly divided into observation group and control group,65 cases in each group.The two groups were treated on the basis of routine treatment.The observation group was treated with Praxol and the control group with bromocriptine. Results After treatment,the scores of“on and off”time,life activity,mental emotion,motor examination and complications in the observation group and the control group were significantly increased(P < 0.05).The effective rate in the observation group was significantly higher than that in the control group(83.08% vs 69.23%,P < 0.05).In terms of complications,the number of dizziness cases in the observation group was significantly lower than that in the control group(P < 0.05). Conclusion Praxol has good efficacy,safety and clinical value in the treatment of Parkinson's disease.It is worthy of further study and popularization.
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